Scientific Programme

Biomechanics & Motor control

IS-BM02 - The power of eccentric contractions on muscle adaptation, remodeling, and function in old age: The positives of negatives

Date: 02.07.2025, Time: 09:30 - 10:45, Session Room: Arengo

Description

Content: In our symposium on eccentric contractions and aging, we will explore the latest insights on how eccentric resistance exercise impacts molecular signalling pathways, adaptation, and muscle form and function in older adults. Eccentric contractions - those involving muscle lengthening under tension - hold unique potential in preserving muscle function and structure as we age. This symposium brings together leading experts who will share cutting-edge research on this important topic. Dr. Colleen Deane will open with her work on the transcriptional responses triggered by eccentric exercise, shedding light on the cellular mechanisms that drive adaptation in aging muscle. Following her, Dr. Martino Franchi will discuss how eccentric contractions influence muscle morphology, with a focus on structural changes and adaptations that can preserve muscle function in old age. Lastly, Dr. Geoff Power will address how eccentric training can stimulate sarcomerogenesis, providing insight into how eccentric stimuli promote sarcomere addition and potentially counteract age-related muscle decline and impairments in muscle mechanical performance. Relevance: This will surely be a thought-provoking session as we examine how eccentric training may serve as a powerful tool to promote and maintain healthy adult aging. Target Audience: Given the basic and applied nature of research being presented, this symposium is geared towards both practitioners and basic scientists.